buy custom Winning the Right War essay

buy custom Winning the Right War essay Abraham Lincoln was a presidential hopeful of the Republican Party during the pro-1860 presidential campaigns. The North and the South differed on very many issues, and on most occasions, the North won. This essay highlights the key causes of the Civil War. Lincoln was elected as the President of the Union on November 6, 1860. Southern states like Alabama, Louisiana, Georgia, Texas, South Carolina, Mississippi, and Florida seceded from the Union and formed the Confederate (Wattenberg, Martin, and Lineberry 77). However, in his inaugural speech, Lincoln stated that he had not intentions of abolishing slavery or the Fugitive Slave Law. This statement angered the Northerners and by mid-April 1861, the Confederacy attacked Fort Sumter, and the federal forces retaliated, marking the launch of the Civil War. The primary factor that led to the war was economic disparities between the North and the South. During his presidential campaign, Lincoln used anti-slavery as his platform, an ideology that did not appeal to the Southerners. The Souths economy was based on plantation agriculture, and their main produce was cotton, a crop that was valued like gold both in the domestic and international market. Owners of huge plantations were very keen to sustain their rich lifestyle, thus; their heavy reliance on slavery. On the contrary, the North relied on industries and commerce and declined to use slavery as a source of labor. Most of the northerners controlled and owned ships, and trade routes, a very lucrative business at the time. They paid for labor and all the expenses in their commercial activities and industries. They felt that the southerners had an unfair edge, over them because they did not pay for labor. This difference in opinion could have been one of the causes that led to the Civil War. Although the South used free slavery, the North was in a better position financialy. The North had nothing to lose because they did not rely on slavery. In the Constitution and Declaration of Independence, all human beings were supposed to be free. Slavery was a very controversial issue because many people especially Northerners did not understand how a nation based on human freedom could allow slavery. Slavery was a key issue in the economic welfare of the South and abolition of the institution was out of order. The second issue involved taxation. The Rights of the Individual States was at risk over the issue of taxation. The Union demanded that, every state should collect taxes and deliver the revenue to the national government. Every state demanded that they should have representatives both in the Congress and in the House of Representatives. Although this happened, there was some element of dissatisfaction among people. Most of the Southerners felt that their voice was not heard in the national government. The South wanted lower taxes and subsidies because they grew crops like cotton that could not thrive in the North. They also felt that, the North priced their agricultural produce lowly, in a bid to control their financial well-being. The third issue was the differences sparked by the federalism versus the anti-federalism debate. In 1787, the novel Constitution was presented for ratification (Kennedy 82). Issues on interpretation of the Bill of Rights, a republic government, and the independence of the states had taken centre stage. This led to the formation of federalists (those who supported the ratification of the new constitution) and the anti-federalist (those against the constitution). Federalists included John Jay, Alexander Hamilton, and James Madison while anti-federalists included Thomas Jefferson, George Clinton, Patrick Henry, and Elbridge Gerry. Federalists wrote articles in support of the Constitution (federalist papers) while anti-federalists wrote articles against the constitution (anti-federalist papers). In 17888, Federalists won, and George Washington was elected President with John Adams as his deputy. They took office in 1789 and went on to establish the first Congress and military machinery. Washington appointed Alex Hamilton as the Treasury Secretary while Thomas Jefferson was appointed as the State Secretary. Federalists like Hamilton wanted a powerful federal government while Jefferson wanted states to have more power than the federal government and a strong Bill of Rights. Hamilton proposed that the national government should clear debts owed by the states while Jefferson opposed because most Southern states had paid while the Northern states were slow in repaying the debt. The debts were paid and the government gave in to the demands of the south by moving the Capital of the Union from New York to the South of River Potomac, the current location of Washington D.C. (Gordon 17). Another main issue that caused extreme political differences between the federalists and anti-federalists was the creation of a national bank. Hamilton and his supporters used a loose clause in Article I to create a national bank. The anti-federalists argued that such a bank would put the elite close to a reserve meant for many people. In case of lack of control, the outcome would be very detrimental to the economy. The anti-federalists also opposed the imposition of tariffs on states. These tariffs were meant to act as a source of revenue for the federal government but the bill did not pass (Wood 536-537). In conclusion, economic issues like the use of slaves in the south led to growing tensions over an unfair labor advantage. The North relied on commerce and controlled the prices of commodities produced by the South. The South felt that they were targeted since they did not have economic subsidies and had to pay taxes. The strength that the Federalists had in the national government was not well accepted by the South and all these factors sparked Civil War. Buy custom Winning the Right War essay

Discover Study Habits That Support Your Learning Style

Discover Study Habits That Support Your Learning Style All students learn through a combination of seeing, hearing, and experiencing. However, for most students, one learning style stands out. Research has shown that students who study in a way that supports their learning style can perform better on tests and  improve their grades. For example, visual learners sometimes struggle during essay exams because they cant recall test material that was presented orally during class. However, if the visual learner uses a visual aid when studying, like a colorful outline of test materials, he or she may retain more information. Read on to discover the characteristics of and ideal learning strategies for each learning style. Visual Learner Characteristics Visual learners are those who learn through seeing. Visual learners typically share the following characteristics: Good at spelling, but forgets first namesFind quiet study time beneficialEnjoy colors and fashionDream in colorUnderstand visual elements and chartsAble to learn sign language easily Learning Suggestions for Visual Learners Draw a map of events in history or draw scientific process.Make outlines of reading assignments.Copy whats on the board.Diagram sentences.Use flashcards.Take notes and make lists.Watch videos.Mark up your notes with highlighters, underlines, and color coding. Test Types for Visual Learners Best test type: Diagram activities, map reading, essay tests, demonstrating a process.Worst test type: Listening tests Auditory Learner Characteristics Auditory learners are those who learn best through hearing. They typically share the following characteristics: Like to read out loudUnafraid to speak up in classGood at giving explanations and oral reportsRemember namesNotice sound effects in moviesEnjoy musicAble to follow spoken directionsStruggle to stay quiet for long periods of timeFocused in study groups Learning Suggestions for Auditory Learners Use word association to remember factsRecord lecturesWatch videosRepeat facts with eyes closedParticipate in group discussionsUse audio for language practiceRead your notes out loud after writing them Test Types for Auditory Learners Best test type: Oral exams and writing responses to lectures.Worst test type: Reading passages and writing answers in a timed test. Kinesthetic Learner Characteristics Kinesthetic learners are those who learn through hands-on experience. Kinesthetic learners typically share the following characteristics: Good at sportsCant sit still for longMay have sloppy handwriting.Learn well through lab and modeling activitiesStudy with loud musicEnjoy adventure books and moviesFidgety during lectures Learning Suggestions for Kinesthetic Learners Study in short blocksTake lab-based classesAct out your study notesTake field trips to reinforce knowledgeStudy in groupsUse flashcards and memory games Test Types for Auditory Learners Best test type: Short definitions, fill-in-the-blank questions, and multiple choice.Worst test type: Essay tests and any overly long tests.

Using Lean Six Sigma to Improve Hospital based, Outpatient Imaging Article

Using Lean Six Sigma to Improve Hospital based, Outpatient Imaging Satisfaction - Article Example Therefore, the paper focuses on improving the service of the imaging department and brings into consideration the expectations of patients regarding the hospital. Unlike any commercial business, where greeting the customer and asking him to pay another visit soon, shall be considered good, such is not the case of the healthcare industry. In order to create an experience in the mind of the patients, service has to be personalized and focused. Previously, the hospital had wrongly focused on the process, procedure, safety and time to deliver the service; however, recent analysis suggested that customer satisfaction is about the consistency in the smooth conduct of the process as well as behavior of the staff. In order to ensure that Methodist achieves its objectives, it has decided to adopt a process that involves six sigma approaches and includes steps that are Define, Measure, Analyze, Improve and Control. Moreover, the customer satisfaction is the function of the service that is delivered to outpatients; therefore, the department has decided to pay special attention to these patients. Furthermore, the hospital uses Press Ganey service to assess its patient’s satisfaction.... The volume modality table seems to confirm the strategy of the hospital as outpatients seems to be the most frequent user of the machinery as compared to others while their share is approximately 50% in the case of Ultrasound, MRI and nuclear medicine. Thus in order to measure the performance in achieving those objectives, a more focused approach was laid down by reviewing the past data of outpatient imaging. The data revealed that the customer’s satisfaction has a very strong correlation with the time that the patient has to wait after being called down to testing area. Thus, based on this finding, a research was conducted that also confirmed the earlier finding. Therefore, the process was redesigned in order to improve efficiency in the system such that the lagging time shall be minimized. This was initiated by forming the workflow of all the four areas involved in the process which includes scheduling, registration, imaging and specific modality. However, more important in this regard was the communication regarding the appointments that were made with the patients since the time can be interpreted in more than one ways, while there used to a background noise that made communication difficult. In this regards, the email system was proposed as the solution to the problem. The most important part is the process of registration which used to take a lot of time due to its complex nature, such was simplified. Further, the outpatient was not being focused upon, as inpatient was being prioritized more over to outpatient regardless of the condition of the patients. To ensure further patient satisfaction, he will be communicated and briefed about the time the tests will start and details related to it. In case, he is late then he can be

Strategic Management Essay Example | Topics and Well Written Essays - 1000 words - 3

Strategic Management - Essay Example These initiatives normally revolve around resource allocation, utilization, and performance in the external environment of the business. Additionally, strategic management provides the opportunity for an organization to specify its mental picture, policies, objectives, mission and plans. It allocates the required resources for the execution of its programs, projects and plans (Sachs & Ru?hli 2011 p. 1). Furthermore, strategic management ensures the organization develops a balanced scorecard for the evaluation of its general performance. The scorecard also enables it to determine if it is progressing towards its set objectives and make the necessary changes or adjustments. However, for an organization to perform its strategic management process successfully, it must have the right paradigm. Importance of an organization’s "paradigm" for strategic management Several contemporary organizations today are operating in complex environments where there are frequent and sudden changes of structures. They need to decamp from their traditional management structures to adapt new approaches to management. Incidentally, the operating environment for most organizations faces stiff competition and massive explosion in the field of information technology. This requires that the company update its management paradigm to fit in the new era adequately (Kachru 2009, p. 48). The enhanced utilization of information technology has led to the emergence of knowledge or information based economy. This is partially responsible for the increase in complexities of organizations. Consequently, many organizations have resorted to changing their paradigms to adopt new organizational structures. This includes the changes in leadership and management practices. Additionally, technologies such as the internet, e-mail, voice mail and telecommuting have also contributed in the rebranding of the structures of organizations to encompass virtual offices, companies and teams (Kachru 2009, p. 92 ). The shift to the new organizational paradigms has several uses to the organization. The adoption of new technologies in the field of information science is making both intra-organizational, as well as inter-organizational communications simpler (Kachru, 2009, p. 93). Consequently, this eliminates the previous communication boundaries leading to a global market place that is borderless. The elimination of the market place boundaries can significantly reduce the command chains within organizational structures and paradigm. As a result, the organization will have free control spans by replacing its departments with stronger teams that have been empowered. This paradigm assumes an organizational structure whereby a flatten hierarchy replaces vertical boundaries as cross-functional teams replace functional departments. This is important to the organization because it consolidates the activities of the organization around centralized processes (Kachru 2009, p. 84). The creation of the organizational paradigms without boundaries eliminates geographical barriers to the organization. This places an organization in a suitable position to interact freely with its clients and other business partners in the entire globe. For good strategic management, an organization needs to shift its paradigm to benefit from the following processes a. Reduced dependence on the leadership of command and control b. Hierarchy breakdown that leads to a lean change in the systems of management c. Enhanced commitment to the application and utilization of virtual technologies d. Increased teamwork reliance e. Attain flexibility f. Interactive system of knowledge transfer through electronic and mutual interest instead of authority systems New forms of management

Samsung Marketing Plan Essay Example for Free

Samsung Marketing Plan Essay Samsung Electronics has proven to the business world that they are one of the mostprestigious technology companies in the industry. With more technology advancements thanour market can handle at this point and time, Samsung has paved the way for the future inelectronics. One of the most popular new â€Å"toys† in the market today, is the unbelievable 3D TV. The first 3D TV was launched in March of 2010, and has already had a major impact on themarket. With the release earlier this year, Samsung dominated the market, controlling nearly90% of the total share. Samsung’s product, the 9000 series TV, is incomparable to competitionwith its ultra-thin screen, measuring only 0. 3 inches in width. The 9000 series also comes with afull color spectrum that makes for an incredible viewing experience. Although Samsung is dominating the 3D market, we still have very detailed strategiesand tactics that we believe will give us an increased competitive advantage over our competition. The company’s main emphasis the past couple years has been on integration,union, and encouraging innovation. Samsung is always preparing for the next big item to hit themarket, which is why their technology is so far ahead of all leading competitors. In the future,we plan to enter the 3D video gaming market with a partnership with Microsoft. This will give usaccess to all of Microsoft’s gaming technology, in which we will combine with our quality of sound and viewing stations to create the ultimate gaming experience. Of course, throughoutour journey through this market, we will continue to provide the best ad campaigns for the publicso that they will never forget our product. We will put as much prominence as possible in thesleek design and the one of a kind ultra-thin panel, only available in the Samsung 9000 series. By having an effective ad campaign, we will be able to catch the eye of many different targetgroups. Our major target groups are men around the ages of mid twenties to late thirties,Caucasian males, with a new and growing family. Studies show that this category is more likelyto buy the TV, along with a gaming system, than other aged males. We are also targeting â€Å"CubeTubers†. This is a group that consists of young people who grasp onto new technology quickly.

Industrial Engineering Essay -- essays research papers fc

Technical Drawing Related Career Report   Ã‚  Ã‚  Ã‚  Ã‚  Industrial Engineers serve as a bridge between management and operations. They combine their solid engineering background with good business sense and management ability. They figure out the best use of facilities, equipment and people for the most cost efficient and productive way to make or process a product. Industrial Engineers concentrate on improving manufacturing productivity and reducing costs associated with inventory. They are also concerned with worker safety and work environment.   Ã‚  Ã‚  Ã‚  Ã‚  In order to be any engineer, you must love math, science and solving problems. Whether it's figuring out how to erect a structurally sound skyscraper, design a more efficient car engine. Engineers at the most basic level are problem solvers. Engineering is a career based on logical, systematic problem solving, generally in high-tech, industrial, or scientific fields. Industrial engineers determine the most effective ways for an organization to use the basic factors of production—people, machines, materials, information, and energy—to make a product or provide a service (Occupational Outlook Hand Book). Engineers apply scientific and technical knowledge to address their problems and tasks faced by businesses and governments.   Ã‚  Ã‚  Ã‚  Ã‚  An Industrial engineer is made up of these characteristics interested in technical and engineering work, good oral and written communi...

Mango (Mangifera Indica) Leaves Extract and Coconut Oil as an Antibacterial Ointment

Mango (Mangifera indica) leaves extract and Coconut Oil as an Antibacterial Ointment A Science Investigatory Project of Kristifany C. Mamba Bansud National High School-Regional Science High School for Region IV – MIMAROPA Pag-asa, Bansud, Oriental Mindoro Abstract The purpose of this study is to produce an antibacterial ointment out of Mango leaves extract and coconut oil. Young mango leaves were gathered and was chopped into small pieces. 50 mL of coconut oil was put in a frying pan. Then, the chopped mango leaves was added to the coconut oil. It was mixed for 10 minutes. Next, the small bits of mango leaves were removed from the coconut oil. Lastly, candle wax was added to the mixture. It was stirred again thoroughly. The solution was transferred into an empty container and left to cool down. The mango leaves extract with coconut oil was tested at the Bureau of Plant Industry. It was tested against the bacteria E. coli and S. aureus. The resulting Numerical value was 2. 5 for E. coli and 3. 0 for S. aureus. The bureau used the standard parameter 1-2- slightly inhibited and 3-5 as partially inhibited. Thus, the inhibition of the mango leaves extract and coconut oil in E. oli was slight and it is partial in S. aureus. The researcher concluded that mango leaves extract with coconut oil can kill bacteria like E. coli and S. aureus. It can also be concluded that it can help wounds heal faster because of its antibacterial property. Chapter I Introduction Background of the Study The Philippines have many different herbal plants that can cure different illne ss like body pain, toothache, arthritis, and other diseases. The herbal plants we have contain helpful constituents and properties that can cure different kinds of diseases. We can make useful product made from these plant and other materials. Nowadays, many herbal plants are being discovered with more uses. Many companies used herbal plants to make ointments, tablets, coffee or teas. Ointments are very useful in treating different kind of wounds. The production of ointments from herbal plants found in our country can help us minimize our dependence on the use of high – cost ointments. The herbal plant must have anti-inflammatory, anti-allergenic and antibacterial properties to produce an effective ointment. Most of the wounds are infected by the common bacteria like Escherichia coli. As the wounds go deeper and become more complex they can infect the underlying muscles and bone causing osteomyelitis. Coliforms and anaerobes are associated with osteomyelitis in those people who have infected wounds. You also see the bacteria Staphylococcus aureus in the infected wound. Local factors that increase chances of wound infection are having large wound area, increased wound depth, degree of chronicity, the body, necrotic tissue, and mechanism of injury (bites, perforated viscus). (Neal R. Chamberlain. n. . ) The mango leaves (Mangifera indica) and coconut oil possesses antibacterial activity against different bacteria. (Research Update of Mango and Mango Leaf Extract, n. d. ). Coconut and olive oils are traditionally used to moisturize and treat skin infections. Extensive research done by scientists such as Jon J Kabara, PhD, has shown that the Lauric acid found in Coconut Oil is a potent antim icrobial agent  . Lauric acid is a major component (49%) of Coconut oil. It has also been found to kill the H. Pylori bacteria  in the stomach which are responsible for many stomach problems such as ulcers. The good thing about Lauric acid is that it doesn't kill friendly bacteria in the stomach. Antibiotics kill both good and bad bacteria in the stomach and often need to be followed with probiotics such as acidophilus bacteria to replenish friendly bacteria in the gut. Objectives General Mangifera indica leaves and coconut oil have anti-bacterial contents which can help remove the infection on the wounds. This study aimed to produce an ointment which can kill the bacteria and cure different types of wounds out of Mangifera indica leaves and coconut oil. Specific This research study was conducted to determine if mango leaves extract and coconut oil can be made into an ointment and if it can help wound heal faster. Statement of the Problem Specifically, this study ought to answer the following questions: 1. Can the ointment made from Mangifera indica leaves extracts and coconut oil kill the bacteria in the wounds? 2. Can the Mangifera indica leaves extract and coconut oil be made into an ointment? 3. Can the ointment made from Mangifera indica leaves and coconut oil extract help the wound to heal faster? Hypothesis 1. The ointment made from Mangifera indica leaves extracts and coconut oil can kill bacteria in the wounds. 2. The extract of Mangifera indica leaves and coconut oil can be made into an ointment for curing wounds. Significance of the Study This study greatly benefits the people in the community who cannot afford to buy expensive ointment for wounds. It can also benefit the hospitals and in small clinics. The additional medication in curing wounds can help a lot to save a life. It has significance to those who were far from the store or drug store because they can cure our wounds without taking too long from buying ointments from far drugstores. It can be also a source of income for the people in provinces. Scope and Limitation This study was limited only on the production of ointments from mango leaves extracts and coconut oil. The ointment produced from mango leaves extracts and coconut oil focuses on killing the bacteria in the wounds. It was limited to use if there is irritation on the skin after the application of the ointment. For the patients who have sensitive skin should ask permission from a doctor before using the ointment. Chapter II Review of Related Literature Review of Related Literature Antibacterial Pertaining to a substance that kills bacteria or inhibits their growth or replication. Antibiotics synthesized chemically or derived from various microorganisms exert their bactericidal or bacteriostatic effect by interfering with the production of the bacterial plasma wall; by interfering with protein synthesis, nucleic acid synthesis, or plasma membrane integrity; or by inhibiting critical biosynthetic pathways in the bacteria. (2009, Elsevier. ) E. coli E. coli  is a common type of  bacteria  that can get into food, like beef and vegetables. E. oli  is short for the medical termEscherichia coli. E. coli  normally lives inside your intestines, where it helps your body break down and digest the food you eat. Unfortunately, certain types (called strains) ofE. coli  can get from the intestines into the blood. This is a rare illness, but it can cause a very serious infection. (Steven Dowshen, MD, August 2009) S. aureus Staphylococci (staph) are Gram-positive s pherical bacteria that occur in microscopic clusters resembling grapes. Bacteriological culture of the nose and skin of normal humans invariably yields staphylococci. In 1884, Rosenbach described the two pigmented colony types of staphylococci and proposed the appropriate nomenclature:  Staphylococcus aureus  (yellow) and  Staphylococcus albus  (white). The latter species is now named  Staphylococcus epidermidis. Although more than 20 species of  Staphylococcus  are described in Bergey's Manual (2001), only  Staphylococcus aureus  and  Staphylococcus epidermidis  are significant in their interactions with humans. S. aureus  colonizes mainly the nasal passages, but it may be found regularly in most other anatomical locales, including the skin, oral cavity and gastrointestinal tract. S. ureus  is often hemolytic on blood agar;  S. epidermidis  is non hemolytic. The bacteria are catalase-positive and oxidase-negative. S. aureus  can grow at a temperature range of 15 to 45 degrees and at NaCl concentrations as high as 15 percent. Nearly all strains of  S. aureus  produce the enzyme coagulase: nearly all strains of  S. epidermidis  lack this enzyme. S. aureus  should always be considered a potential pathogen; most strains of  S. epidermidis  are nonpathogenic and may even play a protective role in humans as normal flora. Staphylococcus epidermidis  may be a pathogen in the hospital environment. Pathogenesis of  S. aureus  infections Staphylococcus aureus  causes a variety of suppurative (pus-forming) infections and toxinoses in humans. It causes superficial skin lesions such as  boils,  styesand  furuncules; more serious infections such as  pneumonia,   mastitis, phlebitis,  meningitis, and  urinary tract infections; and deep-seated infections, such as  osteomyelitis  and  endocarditis. S. aureus  is a major cause of  hospital acquired (nosocomial) infection  of surgical wounds and infections associated with indwelling medical devices. S. aureus  causes  food poisoning  by releasing enterotoxins into food, and  toxic shock syndrome  by release of superantigens into the blood stream. S. ureus  expresses many potential  virulence factors: (1)  surface proteins that promote colonization of host tissues; (2) invasins that promote bacterial spread in tissues (leukocidin,  kinases,  hyaluronidase); (3) surface factors that inhibit phagocytic engulfment (capsule,  Prote in A); (4) biochemical properties that enhance their survival in phagocytes (carotenoids,  catalase production); (5) immunological disguises (Protein A,  coagulase); (6) membrane-damaging toxins that lyse eucaryotic cell membranes (hemolysins, leukotoxin, leukocidin; (7) exotoxins that damage host tissues or otherwise provoke symptoms of disease (SEA-G,  TSST,  ET); and (8) inherent and acquired resistance to antimicrobial agents. Membrane-damaging toxins alpha toxin (alpha-hemolysin)  The best characterized and most potent membrane-damaging toxin of  S. aureus  is alpha toxin. It is expressed as a monomer that binds to the membrane of susceptible cells. Subunits then oligomerize to form heptameric rings with a central pore through which cellular contents leak. In humans, platelets and monocytes are particularly sensitive to alpha toxin. Susceptible cells have a specific receptor for alpha toxin which allows the toxin to bind causing small pores through which monovalent cations can pass. The mode of action of alpha hemolysin is likely by osmotic lysis. ?-toxin  is a sphingomyelinase which damages membranes rich in this lipid. The classical test for ? -toxin is lysis of sheep erythrocytes. The majority of human isolates of  S. aureus  do not express ? -toxin. A lysogenic bacteriophage is known to encode the toxin. (2008 Kenneth Todar, PhD  ) delta toxin  is a very small peptide toxin produced by most strains of  S. aureus. It is also produced by  S. epidermidis. The role of delta toxin in disease is unknown. Leukocidin  is a multicomponent protein toxin produced as separate components which act together to damage membranes. Leukocidin forms a hetero-oligomeric transmembrane pore composed of four LukF and four LukS subunits, thereby forming an octameric pore in the affected membrane. Leukocidin is hemolytic, but less so than alpha hemolysin. Only 2% of all of  S. aureus  isolates express leukocidin, but nearly 90% of the strains isolated from severe dermonecrotic lesions express this toxin, which suggests that it is an important factor in necrotizing skin infections. (2008 Kenneth Todar, PhD  ) Wound Healing Wound healing is a complex process with many potential factors that can delay healing. There is increasing interest in the effects of bacteria on the processes of wound healing. All chronic wounds are colonized by bacteria, with low levels of bacteria being beneficial to the wound healing process. Wound infection is detrimental to wound healing, but the diagnosis and management of wound infection is controversial, and varies between clinicians. There is increasing recognition of the concept of critical colonization or local infection, when wound healing may be delayed in the absence of the typical clinical features of infection. The progression from ound colonization to infection depends not only on the bacterial count or the species present, but also on the host immune response, the number of different species present, the virulence of the organisms and synergistic interactions between the different species. There is increasing evidence that bacteria within chronic wounds live withi n biofilm communities, in which the bacteria are protected from host defences and develop resistance to antibiotic treatment. (Edwards R,  Harding KG Apr. 17, 2004) Bacteria and Wounds Bacteria are ubiquitous in the geography of the human body. In the skin, the average human being harbors at least 200 species of bacteria, totaling more than 1012 organisms. Therefore, when the skin is broken by trauma or disease, bacteria are also ubiquitous in wounds. When discussing the presence of bacteria in an open wound of a human host, three conditions are noted with respect to their presence on or in the tissue, their impact on the healing of the wound, and the associated immune response from the host. The first condition is bacterial contamination or the simple existence of bacteria on the surface of the wound. Contamination is specifically defined as the presence of non-proliferating organisms on the superficial tissues. Contaminating bacteria do not elicit an immune response from the hos t and do not impact the healing process. The second condition, bacterial colonization, is differentiated from contamination in that it refers to proliferating organisms on the wound surface – bacteria that have adhered to the superficial tissues and have begun to form colonies. Colonization is also characterized by a lack of immune response from the host and generally is not believed to impact or interfere with the healing process. 2 Wounds that contain nonviable tissue (ie, slough and/or eschar) offer a particularly hospitable environment for colonization because the dead tissues provide a ready source of nutrients for the growing bacterial colonies. In the third condition, bacterial infection, proliferating bacteria are not only present on the surface of the wound or in nonviable tissue, but have also invaded healthy, viable tissue to such a depth and extent that they elicit an immune response from the host. Local clinical signs of tissue redness, pain, heat, and swelling generally characterize this immune response, along with an increase in exudate production or purulence. Bacterial infection delays and may even halt the healing process. The mechanism of this healing delay involves competition between host cells and bacterial cells for oxygen and nutrients and increased host cell production of inflammatory cytokines and proteases in response to the bacteria and their associated toxins. (Liza Ovington, PhD, CWS, n. d) Related studies In the research update of mango and mango leaf extract, effects of a natural extract from Mangifera indica L, and its active compound, mangiferin, on energy state and lipid peroxidation of red blood cells. Following oxidative stress, modifications of several biologically important macromolecules have been demonstrated. In this study they investigated the effect of a natural extract from Mangifera indica L (Vimang), its main ingredient mangiferin and epigallocatechin gallate (EGCG) on energy metabolism, energy state and malondialdehyde (MDA) production in a red blood cell system. Analysis of MDA, high energy phosphates and ascorbate was carried out by high performance liquid chromatography (HPLC). Under the experimental conditions, concentrations of MDA and ATP catabolites were affected in a dose-dependent way by H(2)O(2). Incubation with Vimang (0. , 1, 10, 50 and 100 mug/mL), mangiferin (1, 10, 100 mug/mL) and EGCG (0. 01, 0. 1, 1, 10 muM) significantly enhances erythrocyte resistance to H(2)O(2)-induced reactive oxygen species production. In particular, they demonstrate the protective activity of these compounds on ATP, GTP and total nucleotides (NT) depletion after H(2)O(2)-induced damage and a reduction of NAD and ADP, which both increase because of the energy consumption following H(2)O(2) addition. Energy charge potential, decreased in H(2)O(2)-treated erythrocytes, was also restored in a dose-dependent way by these substances. Their protective effects might be related to the strong free radical scavenging ability described for polyphenols. Mango and Mango Leaf Extract, n. d. ) Mangifera indica L. extract consists of a defined mixture of components (polyphenols, terpenoids, steroids, fatty acids and microelements). It contains a variety of polyphenols, phenolic esters, flavan-3-ols and a xanthone (mangiferin), as main component. This extract has antioxidant action, antitumor and immunemodulatory effects proved in experimental models in both in vitro and in vivo assays. The present study was performed to investigate the genotoxicity potential activity of Vimang assessed through different tests: Ames, Comet and micronucleus assays. Positive and negative contr ols were included in each experimental series. Histidine requiring mutants of Salmonella typhimurium TA1535, TA1537, TA1538, TA98, TA100 and TA102 strains for point-mutation tests and in vitro micronucleus assay in primary human lymphocytes with and without metabolic activation were performed. Results of Comet assay show that the extract did not induce single strand breaks or alkali-labile sites on blood peripheral lymphocytes of treated animals compared with controls. On the other hand, the results of the micronucleus studies (in vitro and in vivo) show Vimang induces cytotoxic activity, determined as cell viability or PCE/NCE ratio, but neither increased the frequency of micronucleated binucleate cells in culture of human lymphocytes nor in mice bone marrow cells under their experimental conditions. The positive control chemicals included in each experiment induced the expected changes. The present results indicate that M. indica L. extract show evidences of light cytotoxic activity but did not induce a mutagenic or genotoxic effects in the battery of assays used. (Mango and Mango Leaf Extract, n. d. ) Anti-allergic properties of Mangifera indica L. extract (Vimang) and contribution of its glucosylxanthone mangiferin. : Vimang is the brand name of formulations containing an extract of Mangifera indica L. , ethnopharmacologically used in Cuba for the treatment of some immunopathological disorders, including bronchial asthma, atopic dermatitis and other allergic diseases. However, the effects of Vimang on allergic response have not been reported until now. In this study, the effects of Vimang and mangiferin, a C-glucosylxanthone isolated from the extract, on different parameters of allergic response are reported. Vimang and mangiferin show a significant dose-dependent inhibition of IgE production in mice and anaphylaxis reaction in rats, histamine-induced vascular permeability and the histamine release induced by compound 48/80 from rat mast cells, and of lymphocyte proliferative response as evidence of the reduction of the amount of B and T lymphocytes able to contribute to allergic response. In these experiments, ketotifen, promethazine and isodium cromoglicate were used as reference drugs. Furthermore, they demonstrated that Vimang had an effect on an in-vivo model of inflammatory allergy mediated by mast cells. These results constitute the first report of the anti-allergic properties of Vimang on allergic models, as well as suggesting that this na tural extract could be successfully used in the treatment of allergic disorders. Mangiferin, the major compound of Vimang, contributes to the anti-allergic effects of the extract. (Mango and Mango Leaf Extract, n. d. ) Anti-inflammatory, analgesic and hypoglycemic effects of Mangifera indica Linn. (Anacardiaceae) stem-bark aqueous extract.   Previous studies in their laboratories and elsewhere have shown that some members of Anacardiaceae family possess antiinflammatory, analgesic and hypoglycemic effects in man and mammalian experimental animals. The present study was, therefore, undertaken to examine the antiinflammatory, analgesic and antidiabetic properties of the stem-bark aqueous extract of Mangifera indica Linn. , M. indica a member of the Anacardiaceae family, in rats and mice. The stem-bark powder of M. indica was Soxhlet extracted with distilled water and used. M. indica stem-bark aqueous extract (MIE, 50-800 mg/kg i. p. ) produced dose-dependent and significant (p

Qualitative Social Research Essay

Sociological researcher, Steven Taylor, in his articles discusses the moral and ethical issues researchers must grapple with when they are carrying out studies of abusive behavior in institutions that have weak and disadvantaged people in our society. He cites his own 1 year work experience in a state institution for the mentally retarded to highlight his concerns. He describes it as being in deplorable physical condition and grossly understaffed. The attendants had little training and there were no therapy programs. They controlled the inmates through verbal and physical abuse directly to them and forcing them to clean up their own mess, including feces and urine. They also pitted some inmates against others, such as giving and withholding favors of coffee, food and drugs. Further they forced them to perform humiliating acts such as swallowing lit cigarettes and performing fellatio on each other. Mr. Taylor felt that in order to gain the trust of the attendants and thereby get more valid observations, he had to develop a rapport with them. He did so by drinking beer with them and socializing in other ways. He also played the naive student role and refrained from being critical about their methods. Nevertheless, he was troubled by the abusive behavior he witnessed, but in a quandary as to what to do about it. The attendants, for their part, rationalized their behavior by saying â€Å"the inmates don’t hurt like we do† and treating their actions as entertainment. Personally, I suspect they really didn’t know how to properly treat the inmates and were desperate to try anything that seemed to control them at least in the short run. The author then posed the question as to what the researcher should do in the face of this ethical dilemma during his study. He considered 4 alternatives ; 1)intervene. , for example to as attendant to stop or threaten to inform his supervisor. The problem with this approach is that it would spell an end to rapport with the attendants and thereby hinder the researcher’s ability to collect data on daily activities. 2) leave field. But research is needed to learn why people abuse. 3) blow the whistle. This would obviously shatter rapport and violate the confidentiality provisions of the ASA Code of Ethics. 4 continue study- which is what Mr. Taylor did. Obviously he felt that although this might not appear to be a good option it was the â€Å"least bad† to him. The author then suggests 4 ways to deal with immoral acts; 1 participation in abuses. He contends this is never justified, and that research goals can be accomplished without making human subjects suffer. Furthermore it is I clear violation of the ASA Code of Ethics. 2 ) observation of abuse. This may be the price to pay for conducting field research in immoral situations, but a person can never sit idly by in extreme cases like murder and rape. 3 inadvertently contribute to abuse because of reactive effects . It is clear that often this can’t be controlled by the researcher and therefore can’t be resolved by a professional code of ethics. However the researcher can refrain from encouraging it, for example pretending not to hear an invitation to join in such behavior. 4) doing something about abuse after study, that is, by publishing it and trying to get political action especially through mass media such as TV and newspapers. Finally Taylor concludes the researcher should 1) debate moral and ethical issues before embarking on a particular study and 2) make his own assessment about how to resolve professional ethics and personal morality. Reference Taylor, Steven J. â€Å"Observing Abuse. Professional Ethics and Personal Morality in Field Research†

Book Review of The World is Flat, Written by Thomas L. Friedman essays

Book Review of The World is Flat, Written by Thomas L. Friedman essays Hundreds of years ago, Christopher Columbus returned from the New World to the Old World to declare that the world was not flat, but round. Now, in the 21st century, New York Times columnist Thomas Friedman returns from the developing world to the developed world to declare that the world is flat, as flat as that screen on which a budding Indian entrepreneur can host a meeting of his whole supply chain (Friedman 7). By flat, Friedman means that globalization has created a level playing field for more and more of the nations, industries, and individuals in the modern, technologically forward-thinking world. Friedman sees globalization, for all of its problems, as a force for good. It has the power to unite more than it has the power to divide, and to create equality rather than increase the tensions between the haves and the have-nots, as is sometimes alleged. However, although his enthusiasm and vibrant prose is at times infectious, ultimately Friedman seems frighteningly unconcerned about the costs to the developing and the developed world of the unchecked power of multinational companies. Globalization may have benefited some people in the developing world, like the young Indian entrepreneurs, accountants, and engineers that so impress Friedman, but it is questionable if their success can be used to stand for all workers in ever hemisphere of the globe. Friedmans thesis revolves around the proposition that the world is flattening quickly because of convergence of factors. The collapse of the Berlin Wall ended the divisions between the communist and capitalist nations of the world. While the idea that the end of communism as a worldwide movement was a seismic political event is hardly new, Friedman believes that the ability of this advance to break down political and communications barriers between nations in economic terms is just as important as the freedoms and regional instabilities it spawned. &q...

Ionization Energy of the Elements

Ionization Energy of the Elements The ionization energy, or ionization potential, is the energy required to completely remove an electron from a gaseous atom or ion. The closer and more tightly bound an electron is to the nucleus, the more difficult it will be to remove, and the higher its ionization energy will be. Key Takeaways: Ionization Energy Ionization energy is the amount of energy needed to completely remove an electron from a gaseous atom.Generally, the first ionization energy is lower than that required to remove subsequent electrons. There are exceptions.Ionization energy exhibits a trend on the periodic table. Ionization energy generally increases moving from left to right across a period or row and decreases moving top to bottom down an element group or column. Units for Ionization Energy Ionization energy is measured in electronvolts (eV). Sometimes the molar ionization energy is expressed, in J/mol. First vs Subsequent Ionization Energies The first ionization energy is the energy required to remove one electron from the parent atom. The second ionization energy is the energy required to remove a second valence electron from the univalent ion to form the divalent ion, and so on. Successive ionization energies increase. The second ionization energy is (almost) always greater than the first ionization energy. There are a couple of exceptions. The first ionization energy of boron is smaller than that of beryllium. The first ionization energy of oxygen is greater than that of nitrogen. The reason for the exceptions has to do with their electron configurations. In beryllium, the first electron comes from a 2s orbital, which can hold two electrons as is stable with one. In boron, the first electron is removed from a 2p orbital, which is stable when it holds three or six electrons. Both of the electrons removed to ionize oxygen and nitrogen come from the 2p orbital, but a nitrogen atom has three electrons in its p orbital (stable), while an oxygen atom has 4 electrons in the 2p orbital (less stable). Ionization Energy Trends in the Periodic Table Ionization energies increase moving from left to right across a period (decreasing atomic radius). Ionization energy decreases moving down a group (increasing atomic radius). Group I elements have low ionization energies because the loss of an electron forms a stable octet. It becomes harder to remove an electron as the atomic radius decreases because the electrons are generally closer to the nucleus, which is also more positively charged. The highest ionization energy value in a period is that of its noble gas. Terms Related to Ionization Energy The phrase ionization energy is used when discussing atoms or molecules in the gas phase. There are analogous terms for other systems. Work Function - The work function is the minimum energy needed to remove an electron from the surface of a solid. Electron Binding Energy - The electron binding energy is a more generic term for ionization energy of any chemical species. Its often used to compare energy values needed to remove electrons from neutral atoms, atomic ions, and polyatomic ions. Ionization Energy Versus Electron Affinity Another trend seen in the periodic table is electron affinity. Electron affinity is a measure of the energy released when a neutral atom in the gas phase gains an electron and forms a negatively charged ion (anion). While ionization energies may be measured with great precision, electron affinities are not as easy to measure. The trend to gain an electron increases moving from left to right across a period in the periodic table and decreases moving from top to bottom down an element group. The reasons electron affinity typically becomes smaller moving down the table is because each new period adds a new electron orbital. The valence electron spends more time further from the nucleus. Also, as you move down the periodic table, an atom has more electrons. Repulsion between the electrons makes it easier to remove an electron or harder to add one. Electron affinities are smaller values than ionization energies. This puts the trend in electron affinity moving across a period into perspective. Rather than a net release of energy when an electron is gain, a stable atom like helium actually requires energy to force ionization. A halogen, like fluorine, readily accepts another electron.

Legal and Ethical Aspecrts of Delivery Of Health and Social Care Essay

Legal and Ethical Aspecrts of Delivery Of Health and Social Care - Essay Example When handling patients suffering from terminal illnesses, it is my role to ensure that a patient can successfully manage the condition, experience reduced pain, and approach the end of life stages with a positive outlook. Although my intention is to help such patients, complications may occur because of the choices made by the patients. The case of Brian, who is 55 years old and declined to adopt the advice and the equipment presented by me presents an ethical dilemma for any nurse. In this paper, I will discuss Brian’s case study in detail, evaluating, and analysing the case study and presenting my final ethical decision. In addition, the paper will examine the utilitarian ethical principle and weigh it against the respect for autonomy in an effort to help Brian experience quality life despite his condition. Brian, aged 55 years suffers from multiple sclerosis. Multiple sclerosis is a condition that presents adverse effects on an individual’s immune system. Specifically, the disease affects the protective sheath surrounding nerves. As a result, individuals suffering from the disease do not have a normal communication between the brain and the body. As the disease progresses, an individual’s nervous system may deteriorate badly. Usually, there is no cure for multiple sclerosis and patients with the disease have no other choice but to manage their condition. In the case of Brian, the disease has progressed to the level whereby he needs a wheelchair because he cannot walk (Dimond, 2011). Therefore, the disease has served to debilitate him compelling him to rely on my help and other social workers who help him to feed, wash, and get him out of bed occasionally. Worth noting is the fact that Brian does not have any carer at home because his wife suffers from Parkinson’s disease. Since Brian’s condition compels him to stay in bed or the wheelchair for many hours, he is subject to

Create a research portrait of a well-known artist, explain how his or Essay

Create a research portrait of a well-known artist, explain how his or her work responds to particular social issues - Essay Example ject, requiring the artist to spend years painting in wet plaster rather than working on his sculpture or other projects, some might wonder what prompted Michelangelo to undertake this project rather than allowing some other artist the dubious honor. Just how much freedom Michelangelo had in this decision is an often discussed topic. It might also be wondered whether the subject of the painting was determined by Michelangelo himself or the Pope who commissioned him for the project. To more fully appreciate the process that contributed to the creation of the Sistine Ceiling, it is necessary to understand the details regarding the commission of the project, why it was commissioned, why Michelangelo accepted the commission given the difficulties involved, how he met these challenges given the media and subject involved as well as his final assessment of the results. It is widely accepted that Pope Julius II commissioned Michelangelo to paint the Sistine Chapel ceiling as none other had the power and authority to force the artist back to Rome. Michelangelo had fled the city only two years earlier after the Pope first commissioned him to create approximately 40 sculptures in the most lavish Papal tomb designed to date and then refused to honor his portion of the contract. In addition, the work being requested of Michelangelo was painting rather than sculpture which he preferred. Other accounts indicate the idea of having the ceiling completed by Michelangelo was the idea of Donato Bramante, who intended to discredit Michelangelo’s daunting reputation. â€Å"In Michelangelo’s eyes, Bramante had persuaded the pope to abandon the project [of the tomb] by warning him that it was bad luck to have one’s tomb carved during one’s lifetime, and had then proposed an altogether different commission for the sculptor, a task at wh ich he knew Michelangelo could not possibly succeed† (King, 2003, p. 11). Work commenced on the project in 1536 under Pope Paul III and was